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SubscribeThe challenges of liquid biopsies in an era of precision immunotherapy for cancer.
Accurate genomic characterization of tumors has advanced our understanding of cancer pathogenesis and empowered the development of effective treatments. Although great progress has been made, we are only beginning to understand the heterogeneity of tumors and its impact on treatment. Liquid biopsy is an evolving non-invasive technology for obtaining tissue-derived DNA, RNA and circulating tumor cells. With the advent of RNAseq, next-generation sequencing of tumor nucleic acids is achieving maturity as a research tool and its potential impact on precision medicine is emerging. The term “liquid biopsy” refers to the presence of tumor-derived biomolecules in non-tumor tissues. In this review, we discuss the various components of the liquid biopsy, the impact of these components on precision medicine and the emerging technologies that use these components to generate clinically actionable insight.GB Mowing

Schrooted Followers

Sunday, 14 September 2012

So I’m stuck with a kennel for my growing and growing herd of kittens. Surely some place large enough to house everyone safely and comfortably has somewhere to sleep at night? Well, to be honest, there is one thing that comes up a lot in conversation. It’s called a Litter and I’m pretty sure it’s mentioned quite a lot around here. These kittens are growing fast and with them comes potential dangers. The first thing people often think of are:

Litter

But that’s only the first of it, what about:

Litter: the 1st step to good health and being happy

Litter: the answer to every other problem

Litter: an essential ingredient in every dish

Litter: if it’s not litter, what’s it made of?

Maggots

Maggots: the decay that makes the bones brittle and the flesh stringy

Maggots: the rotten egg smell that lingers and makes you wonder how long that smell has been there

Maggots: the blowfly that lays its eggs in the cats waste and hatch into maggots

Poop

Poop: the single most important component of the litter box

Poop: a sign that the kitten is stressed

Poop: the greatest source of diseases

Disease

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