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Category:Audio softwareA review of the literature on the use of ketamine anesthesia for major oral surgical procedures: A narrative synthesis.
Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist that has been widely used for over 40 years. The analgesic effects of the drug are well known, but only a few studies have focused on its effects on general anesthesia. We set out to critically review the evidence on the use of ketamine during general anesthesia in oral and maxillofacial surgery. Following a systematic literature search of PubMed and PubMed Central, we selected studies that investigated the use of ketamine anesthesia in adult patients undergoing major oral surgical procedures. The literature was limited to randomized controlled trials and clinical trials with consecutive enrollment, and single and double-blinded patient and surgeon. Risk of bias was assessed in each study, using both Quality Assessment of Controlled Trial of Interventions (QATI) and Cochrane risk of bias criteria. Two qualitative comparisons were performed (with and without ketamine). The meta-analysis was performed according to the Mantel-Haenszel fixed-effects model using Review Manager software. Of 28 identified studies, eight were included in the meta-analysis. The main outcome measure was the proportion of patients from each group who required additional rescue analgesics. The incidence of patients requiring rescue analgesia was significantly lower in the ketamine group than the control group (relative risk, 0.46; 95% confidence interval, 0.36-0.59; P A Day in the Life of a Skipper
May 7, 2017
There’s only a few hours left until we hit the highway for a day-long cruise around Lake Erie. (Actually, the cruise should only last about 6 hours, but we’ll make up for it with a lot of fun and a good video along the way!) I’m not looking forward to the trip very much (I’m not afraid of storms or water, but I’m not crazy about driving long distances in a vehicle that is far larger than I want to be in a storm), but I’m excited to get out of town and meet
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